Triple Negative Breast Cancer

A diagnosis of triple negative breast cancer means that the three most common types of receptors known to fuel most breast cancer growth estrogen progesterone and the her 2 neu gene are not present in the cancer tumor. The term triple negative breast cancer refers to the fact that the cancer cells don t have estrogen or progesterone receptors and also don t make too much of the protein called her2.

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Think of cancer cells as a house.

Triple negative breast cancer. Triple negative breast cancer tnbc accounts for about 10 15 of all breast cancers. Triple negative breast cancer is cancer that tests negative for estrogen receptors progesterone receptors and excess her2 protein. The cells test negative on all 3 tests.

The front door may have three kinds of locks called receptors. Triple negative breast cancer is a kind of breast cancer that does not have any of the receptors that are commonly found in breast cancer. So triple negative breast cancer does not respond to hormonal therapy medicines or medicines that target her2 protein receptors.

One is for the female hormone estrogen. These results mean the growth of the cancer is not fueled by the hormones estrogen and progesterone or by the her2 protein.

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